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Hallucinogenic mushrooms have shown promise for their medical benefits, but we are only now beginning to understand how they might help to treat depression.

The brains of people taking escitalopram, on the other hand, showed no change in connectivity between the default mode and other brain networks six weeks after treatment started. Regardless of the caveats, these studies are incredibly promising and move us closer to expanding the available treatment options for patients with depression. And we know that patients with higher levels of negative rumination tend to show increased activity of the default mode network compared with other networks at rest – literally becoming less responsive to the world around them. An active connection between these two brain areas is normally a feature of the brain's " default mode network". This network is active when we rest and focus internally, perhaps reminiscing about the past, envisioning the future or thinking about ourselves or others. Previous studies, using functional MRI (fMRI) brain scanning, have shown that psilocybin seems to reduce activity in the medial prefrontal cortex, an area of the brain that helps regulate a number of cognitive functions, including attention, inhibitory control, habits and memory. So there is an urgent need to expand the repertoire of drugs available to people with depression.

The pearlescent tribute to William Collins, which has a solar-powered jukebox, was installed at Sheffield's Shiregreen Cemetery in March. Sheffield City Council ...

Since it was erected, the council said it had tried to contact the family to "discuss the matter". However, ten weeks after the monument was installed, the council said it had no update to share as it continued to reach out to the family. A huge marble memorial to a late father-of-nine remains unchanged months after the council wrote to the family to discuss the monument.

Coldstream Guardsman Mathew Talbot, from Great Barr, suffered fatal injuries during an anti-poaching patrol in May 2019. His family has worked with staff at ...

She added: "We were all so moved by the story that we wanted to have him here with us all of the time." "The thought that the children here, where Matt was happy, are going to carry on with his memory is just wonderful," Mrs Talbot said. The 22-year-old, who "loved the Army", was part of a five-man mixed Malawian and British group and on his first operational tour when he was attacked.